Structure and conformational flexibility of RNA studied by EPR spectroscopy
Pulsed EPR spectroscopy with rigid spin labels will be used to study structure and conformational flexibility (dynamics) of several RNA motives. We will do this as a function of the environment (molecular crowding), the ion concentration and the changes introduced by ligand or protein binding. Additionally, we will extend the EPR methodology to experiments at room temperature and measurements in cells. More
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Address
Institut für Physikalische und Theoretische Chemie N140 / Erdg. / Raum Nr. 0.16
Goethe-University Frankfurt am Main Max-von-Laue-Str. 7 60438 Frankfurt am Main.
Building N140/16
Co-Workers on RNA
Thilo Hetzke
PhD. Student
EPR spectroscopy, structure and dynamics of nucleic acids
Email: hetzke@chemie.uni-frankfurt.de
Phone: +49(0) 69 798 29402
Building: N140/19
Dr. Jörn Plackmeyer
PostDoc
Synthesis
Email: plackmey@chemie.uni-frankfurt.de
Phone: +49(0) 69 798 29444 or 29639
Building: N140/15 or N120/8
Dr. Burkhard Endeward
Staff Scientist
EPR spectroscopy
Email: b.endeward@chemie.uni-frankfurt.de
Phone: +49(0) 69 798 29590
Building: N140/8
ORCID: 0000-0001-7790-1024