Light-responsive riboswitches and miRNA activity
In the upcoming funding period we will continue our collaborative search for a riboswitch against a photoswitchable small molecule and extend our ways to regulate microRNAs with light. In particular we will focus on methods to regulate microRNAs in inner organs of living organisms such as mice but also in plants in collaboration within the CRC. On top of that we want to perfect our tools for the photoregulation of RNA hybridization and apply them to the regulation of RNA G-quadruplexes. More
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Goethe Universität Frankfurt
Max-von-Laue-Str. 7
60438 Frankfurt am Main
Building N160/416
Co-Workers on RNA
Patricia Müller
PhD. Student
Email: mueller@chemie.uni-frankfurt.de
Phone: +49(0) 69 798 42733
Building: N160/B413
Janik Kaufmann
PhD. Student
Photoregulation of RNA, green photocages, therapeutic oligonucleotides
Email: kaufmann@chemie.uni-frankfurt.de
Phone: +49(0) 69 798 42732
Building: N160/B412
Robin Klimek
PhD. Student
Nucleic Acid Chemistry
Email: klimek@chemie.uni-frankfurt.de
Building: N160/B402