Identification of miRNA Targeting Hierarchies in Lymphocyte Development
Post-transcriptional gene regulation by miRNAs plays a fundamental role in many biological processes. The molecular mechanisms of miRNA function and target recognition are only partially understood. Using T-cell development as a defined physiologic model in combination with light-inducible tools and functional genomics, we will address fundamental questions how miRNAs repress a distinct set of functionally relevant target genes in the presence of an overall excess of miRNA response elements. More
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Institute for Molecular Medizine
Haus 75 / 1. OG (= 2nd floor)
Sandhofstrasse 2-4
60528 Frankfurt am Main, Germany
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Heike Kunze-Schumacher
PhD. Student
Email: heike.kunze-schumacher@kgu.de
Phone: +49 (0) 69 6301 85868
Room: 1.206
Nikita Verheyden
PhD. Student
Email: nikita.verheyden@kgu.de
Phone: +49 (0) 69 6301 85868
Room: 1.206
